For those new to my blog, I started a treatment called Equilibrant a little over a month ago. This was at the suggestion of my doctor (Dr. C), who is one of the better known ME/CFS researchers on the West Coast. A summary of Dr. C's theory regarding immune imbalance and Equilibrant is here.
I'm not ready to declare the Equilibrant a resounding success, but I believe it may be working.
I am still ramping up the dosage. Each week, I add one more pill per day. Currently, I'm taking 5 per day, where the maximum dose--and Dr. C's recommendation--is 6.
Before the Equilibrant, my cycle of crashes and recovery was fairly predictable. I would typically experience 3-6 days of crash, followed by 3-6 days of recovery. And the cycle would repeat. Dr. C said that if the Equilibrant is working, the crashes would gradually become less severe and of shorter duration.
In the middle of May, I had a week-long crash that was just as severe and just a long as an average crash before the Equilibrant. But, if we take that crash out of the picture, I've had a pretty good 5 weeks. True to Dr. C's word, I've had many periods of recovery which were followed by what felt like the onset of another crash. But the full-blown crash would never materialize. Instead, a half-baked crash would set in, hang around for a day or two, and then lift.
Another hopeful sign is that I've experienced a brief start-up reaction every time I've increased the dose. Dr. C said this would happen if the Equilibrant was indeed nudging my immune system toward Th1. Within 3-6 hours of increasing the dose, I feel flu-like symptoms. The interesting thing is that the symptoms are a different "flu-like" feeling than when I crash. They come with muscle aches and tenderness in my neck, which is not what I typically experience when I crash.
Having said all that, I still think it's too early to attribute my modest improvements to Equilibrant. I've certainly had other good streaks before the Equilibrant, although maybe not this good. I'll update again in another month or so. Eventually, I'll have my Natural Killer Cell activity tested again, which will provide a more objective measure.