This is one of the clearest and best I've read at least with respect to the role of cytokines—although a bit oversimplied. A highlight is excerpted here, but the whole article is worth perusing if you have time:
Of course, this is just part of the big picture. It doesn't address the endocrine issues, mitochondrial dysfunction, myalgias, neurological issues or any of other symptoms we experience. These other symptoms are only alluded to in the full article as being a downstream result of the "abnormal cytokine cascade" —but it's a good start.
I like how the author begins by relating ME/CFS's origins to a normal cold/flu, which is a great starting place for readers who haven't studied ME/CFS. When explaining ME/CFS to someone who doesn't have it, it helps to start with something they can understand and relate to, and build from there. The next time I have to explain ME/CFS to healthy person, I'll start with this article.