Perhaps I hit upon the right combination of supplements for me by sheer luck. I'm frequently adjusting my medication and supplements at the recommendation of doctors and based on new and changing symptoms. Right now my med./supp. routine is
- 4 Equilibrants per day on weekdays only (pause on weekends for "pulsing" the dose), plus;
- T3 and T4 for hypothyroidism;
- Digestive enzymes with every meal (for SIBO);
- Allimax (a garlic extract) with every meal (for SIBO); and
- Dihydroquercetin (recommeded by Dr. C) as needed for lactic acid buildup and/or histamine.
I eliminated a couple supplements at around the time the neurological symptoms improved, including my multivitamin which contained significant amounts of B12 methylcobalamin. I may have been over-methylating on the multivitamin. The other supplement I eliminated at that time was phosphatidyl choline (PC). I still can't tell if PC helps or hurts—I get mixed results.
I have been occasionally taking caffeine mints (the caffeine never hits the stomach, so it is gentler on the GI tract), which also contain B12 in the form of cyanocobalamin. Based on my genetic profile, cyanocobalamin may be the better form of B12 for me. It does not cause me to over-methylate. (I realize the practice of taking caffeine in any form by a PWME is considered risky by some. I'm taking it cautiously.)
Also, summers are usually better for me, perhaps because there are fewer colds, flues and illnesses floating around and perhaps because moderate amounts of natural Vitamin D from the sun seems to serve me well. But recent summers have not been as good as this one.
The strong shortness of breath (SOB) that was plaguing me in recent years also seems to have abated. I suspect it has something to do with the change in my diet required by SIBO. Something in my previous diet may have been triggering histamine and allergic-like reactions which seemed to lead to SOB and sniffles. I still occasionally experience the SOB, but nothing like before. I think I know now what foods to avoid, particularly grapefruit, avocado, cashews, coffee, dark chocolate and large amounts of kale. At the same time, now when I do try small amounts of those problematic foods, the reaction is nothing like before. Something else seems to have helped abate the SOB and post-nasal drip. When I do seem to have an overflow of histamine, dihyrdoquercetin helps. I previously reported that dihydroquercetin did not help, but I don't think I was paying close enough attention at the time. It's a subtle difference, but I do believe it is real.
Unfortunately, this improvement may have a potential dark side. Throughout this period of increased functionality, the tenderness and swelling in the lymph nodes in my neck seems to have worsened and become more constant. I don't know what this means and I plan to discuss it with my doctor soon, but it tends to temper my enthusiasm about the upswing.