I have no idea if this is related to ME, but for the last 3 days, I have suddenly developed skin sensitivity in three areas on my body: the right side of my stomach, the right side of my lower back (directly opposite the patch on the stomach), and an area on the back of my right thigh. There are no visible scratches, rashes, or bumps. In terms of the pain sensation, it feels like those areas have been scratched by sandpaper, and now they are sensitive even to the contact of clothing over them. I applied a topical over-the-counter steroid this morning, but it hasn't seemed to help.
I can't recall ever reading that sensitive skin was a major symptom of ME, but then again, I've probably read and forgotten an encyclopedia's worth of information on ME in the last 5 years. A very brief Google search revealed that these types of non-visible skin irritations occur for all sorts of reasons: an irritant, such as new soap, new laundry detergent, contact with chemicals, airborne pollutants, or simply stress.
None of these factors seem to fit. I did switch to a new brand of soap about three weeks ago, so it's possible the soap had a delayed effect. More likely, I think I probably overdid the activity this weekend and my body is reacting with increased cortisol and, thus, stress. I hope this doesn't become a regular part of my entomology.