When packing for the trip, I remembered all of my supplements except D-Ribose. I usually take 5g of Ribose twice a day. By the time Sunday morning rolled around, I'd missed two doses and was feeling a type of malaise that I hadn't felt since before I started taking Ribose back in November. I was shocked at how quickly the effects set in. It's scary to think that my ability to function on a semi-adequate level each day may be due to this one supplement. It's as if the Ribose, alone, is artificially propping me up enough to do my limited daily activities.
When we reached home late Sunday afternoon, I immediately took 5g of Ribose and felt a return to "normal" within a half hour. That will be the last time I forget to bring the Ribose when I leave the house!
The other revelation I had is that SAM-e is powerful, and needs to be taken with plenty of potassium. I've been on Fredd's active B12 protocol since February, but had not added any of the optional cofactors, such as SAM-e, until last week. Fredd is clear that one needs to watch his/her potassium levels when increasing dosage of B12, or when adding cofactors. I thought I had covered my bases by increased my potassium intake by 400mg/day at the same time as the SAM-e. This was clearly not enough. Beginning Friday, I came down with the same neuro symptoms - the same crushing brain fog and muscles twitches - that I'd experienced when I first started taking B12 back in February. So I backed off of the SAM-e and B12 yesterday, and increased my potassium intake, and by today the neuro symptoms had almost completely disappeard.